Aline Rodrigues Hoffmann,
Associate Professor, Anatomic Pathology Service Chief
Department:
Department of Comparative, Diagnostic & Population Medicine
Business Email:
aline.hoffmann@ufl.edu
About Aline Rodrigues Hoffmann
I am a board certified veterinary anatomic pathologist involved and dedicated to research, diagnostic pathology, and training of professional students and veterinary anatomic pathology residents. I am particularly interested and passionate about dermatopathology and fungal diagnostics. I am committed to improvement of animal health and have focused my research career on investigating the role the skin microbiome plays in health and disease in companion animals, pathogenesis of infectious diseases, basic dermatopathology, and microbiology. A special area of my research interest is the development of molecular diagnostics for identification of fungal organisms in formalin fixed paraffin embedded tissues and cytology slides. Through many collaborations, I have supported toxicology studies, in particular investigating the effects of air pollution in animal models.
Accomplishments
Mid Career Excellence Award for Diagnostics
2023
·
American College of Veterinary Pathologists
Clinical Service Award
2015
·
Veterinary Medical Teaching Hospital, Texas A&M University
John Paul Delepane Award
2011
·
College of Veterinary Medicine & Biomedical Sciences, Texas A&M University
ACVP Young Investigator Award – Experimental disease and Industrial and Toxicology Pathology, 2nd Place “Target cells infected by Cache Valley Virus in the ovine fetus"
2010
·
61st Annual Meeting of The American College of Veterinary Pathologists, Baltimore, MD
Graduate Student Scholarship Award
2009-2010
·
College of Veterinary Medicine & Biomedical Sciences, Texas A&M University
L.P. Jones Pathology Resident Award
2009
·
College of Veterinary Medicine & Biomedical Sciences, Texas A&M University
ACVP/AAVLD Diagnostic Pathology Travel Award “Central nervous system pathology of naturally ocurring Trypanosoma evansi infection in horses”
2007
·
58th Annual Meeting of The American College of Veterinary Pathologists, Savannah, GA.
Teaching Profile
Courses Taught
2021-2025
VEM5751 Anatomic Path Core Clerkship
2022-2025
VEM5851 Adv. Anatomic Pathology Clerkship
2022-2025
VEM5162 Vet Pathology 2
2025
VME7980 Research for Doctoral Dissertation
2025
VEM5164 Small Anim Pathology
Board Certifications
-
Veterinary Anatomic PathologistAmerican College of Veterinary Pathologists
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0001-6148-2531
Areas of Interest
- Dermatopathology
- Environmental Toxicology
- Fungal Diagnostics
- Skin Microbiome
Publications
Academic Articles
2025
Staphylococcus felisC4 exhibits in vitro antimicrobial activity against methicillin‐resistant Staphylococcus pseudintermedius in a novel canine skin explant model
Veterinary Dermatology.
36(1):24-33
[DOI] 10.1111/vde.13308.
2024
Considerations for performing companion animal skin microbiome studies.
Veterinary dermatology.
35(4):367-374
[DOI] 10.1111/vde.13250.
[PMID] 38654617.
2024
Facial and systemic mucormycosis caused by Lichtheimia corymbifera in a goat: case report and literature review of fungal infections in goats.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
36(3):463-467
[DOI] 10.1177/10406387241236751.
[PMID] 38465904.
2024
Immune‐mediated panniculitis, folliculitis and vasculitis in a young Shar‐Pei dog treated using a multimodal approach with hyperbaric oxygen, pentoxifylline and corticosteroids
Veterinary Record Case Reports.
[DOI] 10.1002/vrc2.1063.
2024
Telangiectatic osteosarcoma in four dogs: Cytologic, histopathologic, cytochemical, and immunohistochemical findings.
Veterinary clinical pathology.
53(1):85-92
[DOI] 10.1111/vcp.13338.
[PMID] 38418390.
2023
Case report: Intraneural perineurioma in dogs: a case series and brief literature review.
Frontiers in veterinary science.
10
[DOI] 10.3389/fvets.2023.1233230.
[PMID] 38274660.
2023
Common superficial and deep cutaneous bacterial infections in domestic animals: A review.
Veterinary pathology.
60(6):796-811
[DOI] 10.1177/03009858231176558.
[PMID] 37264789.
2023
Cutaneous phaeohyphomycosis in a greater bulldog bat (Noctilio leporinus) in northeastern Brazil.
Journal of comparative pathology.
201:37-40
[DOI] 10.1016/j.jcpa.2022.12.013.
[PMID] 36701871.
2023
Hyphae, pseudohyphae, yeasts, spherules, spores, and more: A review on the morphology and pathology of fungal and oomycete infections in the skin of domestic animals.
Veterinary pathology.
60(6):812-828
[DOI] 10.1177/03009858231173715.
[PMID] 37222139.
2023
Maternal exposure to ultrafine particles enhances influenza infection during pregnancy.
Particle and fibre toxicology.
20(1)
[DOI] 10.1186/s12989-023-00521-1.
[PMID] 37069680.
2023
Paraconiothyrium cyclothyrioides, a novel cutaneous fungal pathogen in a dog and a cat.
Veterinary dermatology.
34(4):363-366
[DOI] 10.1111/vde.13155.
[PMID] 36919229.
2023
Skin biopsy guidelines: tips and advice from veterinary pathologists to practitioners.
Journal of the American Veterinary Medical Association.
261(S1):S114-S121
[DOI] 10.2460/javma.22.12.0586.
[PMID] 37037420.
2023
The feline skin microbiome: interrelationship between health and disease.
Journal of feline medicine and surgery.
25(7)
[DOI] 10.1177/1098612X231180231.
[PMID] 37404049.
2023
Tolerability and the effect on skin Staphylococcus pseudintermedius density of repeated diluted sodium hypochlorite (bleach) baths at 0.005% in healthy dogs.
Veterinary dermatology.
34(6):489-494
[DOI] 10.1111/vde.13186.
[PMID] 37357372.
2022
An ancient haplotype containing antimicrobial peptide gene variants is associated with severe fungal skin disease in Persian cats
PLOS Genetics.
18(2)
[DOI] 10.1371/journal.pgen.1010062.
[PMID] 35157719.
2021
Characterization of staphylococcal communities on healthy and allergic feline skin.
Veterinary dermatology.
32(1):61-e10
[DOI] 10.1111/vde.12885.
[PMID] 32991044.
2021
Characterization of the cutaneous mycobiota in Persian cats with severe dermatophytosis.
Veterinary dermatology.
32(4):319-e88
[DOI] 10.1111/vde.12969.
[PMID] 34033174.
2021
Cytokine expression in feline allergic dermatitis and feline asthma.
Veterinary dermatology.
32(6):613-e163
[DOI] 10.1111/vde.13022.
[PMID] 34519120.
2021
Pyogranulomatous panniculitis in a domestic cat associated with Pseudomonas luteola infection.
Veterinary dermatology.
32(1):83-e15
[DOI] 10.1111/vde.12893.
[PMID] 32991013.
2020
Characterization of Cutaneous Bacterial Microbiota from Superficial Pyoderma Forms in Atopic Dogs.
Pathogens (Basel, Switzerland).
9(8)
[DOI] 10.3390/pathogens9080638.
[PMID] 32781634.
2020
Retrospective Analysis of Aetiological Agents Associated with Pulmonary Mycosis Secondary to Enteric Salmonellosis in Six Horses by Panfungal Polymerase Chain Reaction.
Journal of comparative pathology.
174:1-7
[DOI] 10.1016/j.jcpa.2019.10.002.
[PMID] 31955794.
2019
Distribution of Viral Antigen and Inflammatory Lesions in the Central Nervous System of Cockatiels (Nymphicus hollandicus) Experimentally Infected with Parrot Bornavirus 2
Veterinary Pathology.
56(1):106-117
[DOI] 10.1177/0300985818798112.
2019
Histoplasmosis and multicentric lymphoma in a Nubian goat.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
31(5):770-773
[DOI] 10.1177/1040638719868810.
[PMID] 31378198.
2019
Pathology in Practice.
Journal of the American Veterinary Medical Association.
255(3):313-316
[DOI] 10.2460/javma.255.3.313.
[PMID] 31298639.
2019
The feline cutaneous and oral microbiota are influenced by breed and environment.
PloS one.
14(7)
[DOI] 10.1371/journal.pone.0220463.
[PMID] 31361788.
2019
The skin microbiome of vertebrates.
Microbiome.
7(1)
[DOI] 10.1186/s40168-019-0694-6.
[PMID] 31122279.
2018
Novel association of Psychrobacter and Pseudomonas with malodour in bloodhound dogs, and the effects of a topical product composed of essential oils and plant-derived essential fatty acids in a randomized, blinded, placebo-controlled study.
Veterinary dermatology.
29(6):465-e158
[DOI] 10.1111/vde.12689.
[PMID] 30251442.
2018
Pulmonary and systemic fungal infections in an Atlantic spotted dolphin and a Bryde’s whale, Brazil.
Diseases of aquatic organisms.
128(1):73-79
[DOI] 10.3354/dao03207.
[PMID] 29565255.
2017
Are anti-ganglioside antibodies associated with proventricular dilatation disease in birds?
PeerJ.
5
[DOI] 10.7717/peerj.3144.
[PMID] 28413724.
2017
Atypical cutaneous cryptococcosis in four cats in the USA.
Veterinary dermatology.
28(4):405-e97
[DOI] 10.1111/vde.12423.
[PMID] 28133852.
2017
Chaetomiaceae Fungi, Novel Pathogens of Equine Neurotropic Phaeohyphomycosis.
Veterinary pathology.
54(5):813-819
[DOI] 10.1177/0300985817712558.
[PMID] 28578629.
2017
Characterization of the cutaneous mycobiota in healthy and allergic cats using next generation sequencing.
Veterinary dermatology.
28(1):71-e17
[DOI] 10.1111/vde.12373.
[PMID] 27553477.
2017
Interobserver Agreement Using Histological Scoring of the Canine Liver.
Journal of veterinary internal medicine.
31(3):778-783
[DOI] 10.1111/jvim.14684.
[PMID] 28295598.
2017
Nano-curcumin safely prevents streptozotocin-induced inflammation and apoptosis in pancreatic beta cells for effective management of Type 1 diabetes mellitus.
British journal of pharmacology.
174(13):2074-2084
[DOI] 10.1111/bph.13816.
[PMID] 28409821.
2017
The cutaneous ecosystem: the roles of the skin microbiome in health and its association with inflammatory skin conditions in humans and animals.
Veterinary dermatology.
28(1):60-e15
[DOI] 10.1111/vde.12408.
[PMID] 28133874.
2017
The feline skin microbiota: The bacteria inhabiting the skin of healthy and allergic cats.
PloS one.
12(6)
[DOI] 10.1371/journal.pone.0178555.
[PMID] 28575016.
2016
Canine and Human Atopic Dermatitis: Two Faces of the Same Host-Microbe Interaction.
The Journal of investigative dermatology.
136(6):1087-1089
[DOI] 10.1016/j.jid.2016.03.015.
[PMID] 27212648.
2016
Serum C-reactive protein and S100A12 concentrations in dogs with hepatic disease.
The Journal of small animal practice.
57(9):459-64
[DOI] 10.1111/jsap.12504.
[PMID] 27271454.
2016
The Microbiome: The Trillions of Microorganisms That Maintain Health and Cause Disease in Humans and Companion Animals.
Veterinary pathology.
53(1):10-21
[DOI] 10.1177/0300985815595517.
[PMID] 26220947.
2016
The skin microbiome in allergen-induced canine atopic dermatitis.
Veterinary dermatology.
27(5):332-e82
[DOI] 10.1111/vde.12366.
[PMID] 27485242.
2015
What is living on your dog’s skin? Characterization of the canine cutaneous mycobiota and fungal dysbiosis in canine allergic dermatitis.
FEMS microbiology ecology.
91(12)
[DOI] 10.1093/femsec/fiv139.
[PMID] 26542075.
2014
Immunization with a Borrelia burgdorferi BB0172-derived peptide protects mice against lyme disease.
PloS one.
9(2)
[DOI] 10.1371/journal.pone.0088245.
[PMID] 24505447.
2014
Immunohistochemical expression of ionized calcium binding adapter molecule 1 in cutaneous histiocytic proliferative, neoplastic and inflammatory disorders of dogs and cats.
Journal of comparative pathology.
151(4):347-51
[DOI] 10.1016/j.jcpa.2014.07.003.
[PMID] 25172051.
2014
The skin microbiome in healthy and allergic dogs.
PloS one.
9(1)
[DOI] 10.1371/journal.pone.0083197.
[PMID] 24421875.
2013
Ovine fetal immune response to Cache Valley virus infection.
Journal of virology.
87(10):5586-92
[DOI] 10.1128/JVI.01821-12.
[PMID] 23468505.
2012
Identification of the target cells and sequence of infection during experimental infection of ovine fetuses with Cache Valley virus.
Journal of virology.
86(9):4793-800
[DOI] 10.1128/JVI.06858-11.
[PMID] 22379096.
Grants
Jan 2025
ACTIVE
Interaction between dietary taurine and microbiota sulfur metabolism in the development of colorectal cancer
Role: Co-Investigator
Funding: NATL INST OF HLTH NCI
Oct 2024
ACTIVE
Whole Genome Sequencing of Pythium insidiosum, Lagenidium giganteum forma caninum and Paralagenidium karlingii, and Development of a Quantitative Real Time Polymerase Chain Reaction (qPCR) for Oomycosis Diagnosis in Dogs
Role: Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
Aug 2023
ACTIVE
Improving the Diagnosis of Cutaneous and Mucocutaneous Oomycosis in FFPE samples and cytological preparations from Dogs, Cats and Horses
Role: Principal Investigator
Funding: INTL SOC OF VETERINARY DERMATOPATHOLOGY
May 2023
ACTIVE
Evaluation of the effects of diluted sodium hypochlorite on skin microbiome in dogs with superficial pyoderma and atopic dermatitis: a single blinded, randomized, controlled clinical trial
Role: Co-Project Director/Principal Investigator
Funding: AMER KENNEL CLUB CANINE HLTH FOU
Dec 2021
– Oct 2023
Mechanisms of Particulate Matter Driven Infant Respiratory Disease
Role: Principal Investigator
Funding: TEXAS A&M UNIV COLLEGE STATION & HSC
via NATL INST OF HLTH NIEHS
Jul 2018
ACTIVE
Role of Bacteria in Colitis-Associated Colon Cancer
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDDK
Education
PhD
2011
·
Texas A&M University
Residency in Anatomic Pathology
2009
·
Texas A&M University
Master of Science
2006
·
Universidade Federal de Santa Maria (Brazil)
Veterinary Medicine
2004
·
Universidade Federal de Santa Maria (Brazil)
Contact Details
Emails:
- Business:
- aline.hoffmann@ufl.edu
Addresses: